The resolution of conventional optical microscopes is limited by light diffraction to about 200nm. Several superresolution techniques have been developed to overcome this limit. Among them, SIM (structured illumination microscopy) is one of the most suited for biological imaging.
The openSIM is an add-on designed at the Laboratory for Bio- and Nano- Instrumentation (LBNI, EPFL) to upgrade conventional fluorescence microscopes for superresolution imaging. ****The openSIM is an open-source hardware project which has been designed specifically so that it can be built easily by other researchers using the documentation which we provide in the following (see below). Our goal is to reach labs worldwide and build a vibrant open-hardware community.
Since different platforms have specific advantages we distributed the openSIM documentation on three different platforms based on the information/data which we provide there.
General structure of the openSIM documentation:
<aside> ➡️ Link to GitHub repository
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<aside> ➡️ Link to Zenodo repository
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Please first visit this page to find more information on how to navigate the openSIM documentation: